Enantioselective reduction of oxime ethers with borane catalyzed by polymer-supported 2-piperazinemethanol

S Itsuno, T Matsumoto, D Sato…

文献索引：Itsuno, Shinichi; Matsumoto, Takeshi; Sato, Daisuke; Inoue, Tsutomu Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5879 - 5881

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被引用次数: 46

摘要

The enantioselective reduction of the CdN double bond is an important synthetic strategy for the preparation of optically active amines and has received much attention over the past few years, in both academic and industrial research. 1, 2 Recently, we described new chiral ligands derived from enantiopure 2-piperazinemethanol, which are effectively used for the borane reduction of imines and oximes as well as ketones. 3 For example, by using (S)-4-( ...