Tetrahedron letters

(R)-and (S)-2-acetoxy-1, 1, 2-triphenylethanol-effective synthetic equivalents of a chiral acetate enolate

M Braun, R Devant

文献索引：Braun, Manfred; Devant, Ralf Tetrahedron Letters, 1984 , vol. 25, # 44 p. 5031 - 5034

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被引用次数: 94

摘要

Despite of the impressive progress made in stereoselective aldol reactions , the problem of the addition of an (u-unsubstituted) acetate enolate 1 to al- dehydes in order to give enantiomerically pure B-hydroxycarboxylic acids 2 could not be resolved, although many chira1 auxiliary groups X* were em- 2,3) ployea . In this communication, we describe stereoselective aldol re- actions, using the dianion 3 of (R)-2-acetoxy-1,1,2-triphenylethanol (2) as an easily ...