Bioorganic & medicinal chemistry letters

Use of whole cell culture of Aeromonas sp. as enantioselective scavenger: A facile preparation of l-amino acid derivatives in high enantiomeric excess

Z Zhang

文献索引：Zhang, Zizhang Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 4 p. 1129 - 1131

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摘要

The bacterium Aeromonas sp.(CGMCC 2226) can enantioselectively scavenge d-isomer, making l-amino acid derivatives (AADs) in high ee. The enantioselective scavenger (ES) has shown a broad substrate scope. Eleven l-AADs, Phe derivatives substituted with methyl-, mono-and dichloro-, bromo-, and nitro-group, were produced in high ee from corresponding racemates.