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Synthesis of potent and highly selective inhibitors of human tryptase

WA Slusarchyk, SA Bolton, KS Hartl, MH Huang…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3235 - 3238

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被引用次数: 46

摘要

... Bioorganic & Medicinal Chemistry Letters. ... The tryptase inhibition, selectivities, and chemical stability for the new conformationally constrained guanidino compounds are shown in Table 1 and Table 2. Table 1 displays several constrained guanidino analogues of ...