Four distinct triptycene-containing metal–organic frameworks, including three that are structural isomers, were synthesized and characterized. Structural isomerism was observed in the secondary building units of TMOF-2 giving rise to no fewer than three distinct [Zn4O] 6+ clusters. Structural integrity upon guest solvent removal was confirmed using powder X- ray diffraction and thermogravimetric analysis, but gas adsorption experiments were ...