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Thioxanthene derivatives with neurotropic activity; synthesis of 9-(3-dimethylaminopropylidene)-2-(methylthiomethyl) thioxanthene and of some related compounds

V Kmoníček, V Bártl, M Protiva

文献索引:Kmonicek; Bartl; Protiva Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 7 p. 1722 - 1730

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被引用次数: 0

摘要

Abstract A reaction of 2-(bromomethyl) thioxanthone with sodium methanethiolate with sodium methanethiolate gave 2-(methylthiomethyl) thioxanthone (II) which was transformed by treatment with 3-dimethylaminopropylmagnesium chloride to the tertiary alcohol IV. Its dehydration by heating with dilute sulfuric acid afforded the title compound I. An attempt at preparing the analogous 2-(methoxymethyl) derivative proceeded similarly but failed in ...