Synthetic communications

Efficient synthesis of deoxybenzoins from chalcones

P Mathew, D Mathew, CV Asokan

文献索引：Mathew, Paulson; Mathew, Daliya; Asokan Synthetic Communications, 2007 , vol. 37, # 5 p. 661 - 665

全文：HTML全文

被引用次数: 17

摘要

Abstract β??Ketoaldehydes derived from chalcone epoxides by Lewis acid–catalyzed rearrangement underwent smooth deformylation when refluxed in tetrahydrofuran (THF) in the presence of ethylenediamine, affording deoxybenzoins in excellent yields. The method is general and useful for the preparation of deoxybenzoins with a variety of substitution patterns.