Potent, selective, and orally bioavailable inhibitors of the mammalian target of rapamycin kinase domain exhibiting single agent antiproliferative activity

MFT Koehler, P Bergeron, E Blackwood…

文献索引：Journal of Medicinal Chemistry, , vol. 55, # 24 p. 10958 - 10971

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被引用次数: 11

摘要

... Journal of Medicinal Chemistry. ... of Translational Oncology, § Department of Structural Biology, ∥ Department of Small Molecule Biochemical Pharmacology, # Department of Drug Metabolism and Pharmacokinetics, and ∇ Department of Protein Chemistry, Genentech, Inc., 1 ...