Synthesis

One-pot synthesis of β-amino/β-hydroxy selenides and sulfides from aziridines and epoxides

V Ganesh, S Chandrasekaran

文献索引：Ganesh, Venkataraman; Chandrasekaran, Srinivasan Synthesis, 2009 , # 19 p. 3267 - 3278

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被引用次数: 1

摘要

Abstract Diaryl disulfides and diselenides undergo facile cleavage on treatment with rongalite (sodium hydroxymethanesulfinate) to generate the corresponding thiolate and selenolate species in situ, which effect the ring opening of aziridines and epoxides in a regioselective manner. A simple, mild, cost-effective protocol has been developed to prepare β-amino and β-hydroxy sulfides and selenides in a one-pot operation.