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N*-N*-S* tridentate ligand system as potential antitumor agents

…, G Cristalli, P Franchetti, M Grifantini…

文献索引：Antonini, Ippolito; Claudi, Francesco; Cristalli, Gloria; Franchetti, Palmarisa; Grifantini, Mario; Martelli, Sante Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1181 - 1184

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被引用次数: 48

摘要

The 2, 2'-bipyridyl-6-carbonitrile (6) was prepared by reacting 2, 2'-bipyridyll-oxide (5) with sodium cyanide and benzoyl chloride in water; 5 was synthesized by oxidizing 2, 2'-bipyridyl with H202 in AcOH (Scheme 11). This method gave a higher total yield and used fewer steps than the one described by Case. lo

 相关合成线路
2,2'-联吡啶结构式

366-18-7

2,2'-联吡啶

~%

[2,2'-Bipyridine]-6-carbothioamide结构式

78797-02-1

[2,2'-Bipyridin...

硫代氨基脲结构式

79-19-6

硫代氨基脲

6-(diacetoxymethyl)pyridine-2-carbothioamide结构式

78797-07-6

6-(diacetoxymet...

~70%

6-[(carbamothioylhydrazinylidene)methyl]pyridine-2-carbothioamide结构式

78797-11-2

6-[(carbamothio...

2-cyano-6-(diacetoxymethyl)pyridine结构式

78797-06-5

2-cyano-6-(diac...

~%

6-[(carbamothioylhydrazinylidene)methyl]pyridine-2-carbothioamide结构式

78797-11-2

6-[(carbamothio...

6-(diacetoxymethyl)pyridine-2-carbothioamide结构式

78797-07-6

6-(diacetoxymet...

~45%

2-Pyridinecarbothioamide,6-formyl-结构式

78797-08-7

2-Pyridinecarbo...

2-cyano-6-(diacetoxymethyl)pyridine结构式

78797-06-5

2-cyano-6-(diac...

~%

2-Pyridinecarbothioamide,6-formyl-结构式

78797-08-7

2-Pyridinecarbo...

2-cyano-6-(diacetoxymethyl)pyridine结构式

78797-06-5

2-cyano-6-(diac...

~%

2-Pyridinecarbothioamide,6-[(phenylimino)methyl]-结构式

78797-13-4

2-Pyridinecarbo...

6-(diacetoxymethyl)pyridine-2-carbothioamide结构式

78797-07-6

6-(diacetoxymet...

2,4,6-三溴苯胺结构式

74497-02-2

2,4,6-三溴苯胺

~31%

2-Pyridinecarbothioamide,6-[(phenylimino)methyl]-结构式

78797-13-4

2-Pyridinecarbo...

未登录结构式

4426-72-6

未登录

6-(diacetoxymethyl)pyridine-2-carbothioamide结构式

78797-07-6

6-(diacetoxymet...

~71%

Hydrazinecarboxamide,2-[[6-(aminothioxomethyl)-2-pyridinyl]methylene]-结构式

78797-10-1

Hydrazinecarbox...

2-cyano-6-(diacetoxymethyl)pyridine结构式

78797-06-5

2-cyano-6-(diac...

~%

Hydrazinecarboxamide,2-[[6-(aminothioxomethyl)-2-pyridinyl]methylene]-结构式

78797-10-1

Hydrazinecarbox...

2,2'-二吡啶-6-甲腈结构式

4392-85-2

2,2'-二吡啶-6-甲腈

二甲胺结构式

124-40-3

二甲胺

~50%

[2,2'-Bipyridine]-6-carbothioamide,N,N-dimethyl-结构式

78797-04-3

[2,2'-Bipyridin...

2,2'-联吡啶结构式

366-18-7

2,2'-联吡啶

~%

[2,2'-Bipyridine]-6-carbothioamide,N,N-dimethyl-结构式

78797-04-3

[2,2'-Bipyridin...

2,2-二吡啶基N-氧化物结构式

33421-43-1

2,2-二吡啶基N-氧化物

~%

[2,2'-Bipyridine]-6-carbothioamide,N,N-dimethyl-结构式

78797-04-3

[2,2'-Bipyridin...

盐酸苯肼结构式

59-88-1

盐酸苯肼

6-(diacetoxymethyl)pyridine-2-carbothioamide结构式

78797-07-6

6-(diacetoxymet...

~63%

2-Pyridinecarbothioamide,6-[(2-phenylhydrazinylidene)methyl]-结构式

78797-12-3

2-Pyridinecarbo...

2-cyano-6-(diacetoxymethyl)pyridine结构式

78797-06-5

2-cyano-6-(diac...

~%

2-Pyridinecarbothioamide,6-[(2-phenylhydrazinylidene)methyl]-结构式

78797-12-3

2-Pyridinecarbo...

2,2'-二吡啶-6-甲腈结构式

4392-85-2

2,2'-二吡啶-6-甲腈

氨基甲烷结构式

74-89-5

氨基甲烷

~79%

[2,2'-Bipyridine]-6-carbothioamide,N-methyl-结构式

78797-03-2

[2,2'-Bipyridin...

2,2'-联吡啶结构式

366-18-7

2,2'-联吡啶

~%

[2,2'-Bipyridine]-6-carbothioamide,N-methyl-结构式

78797-03-2

[2,2'-Bipyridin...

2,2-二吡啶基N-氧化物结构式

33421-43-1

2,2-二吡啶基N-氧化物

~%

[2,2'-Bipyridine]-6-carbothioamide,N-methyl-结构式

78797-03-2

[2,2'-Bipyridin...

(3-oxobutan-2-ylideneamino)thiourea结构式

7274-56-8

(3-oxobutan-2-y...

苯肼结构式

100-63-0

苯肼

~62%

[[(3Z)-3-(phenylhydrazinylidene)butan-2-ylidene]amino]thiourea结构式

78797-15-6

[[(3Z)-3-(pheny...

6-(diacetoxymethyl)pyridine-2-carbothioamide结构式

78797-07-6

6-(diacetoxymet...

~76%

2-Pyridinecarbothioamide,6-[(hydroxyimino)methyl]-结构式

78797-09-8

2-Pyridinecarbo...

2-cyano-6-(diacetoxymethyl)pyridine结构式

78797-06-5

2-cyano-6-(diac...

~%

2-Pyridinecarbothioamide,6-[(hydroxyimino)methyl]-结构式

78797-09-8

2-Pyridinecarbo...


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