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Identification of amides derived from 1H-pyrazolo [3, 4-b] pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)

X Zheng, KW Bair, P Bauer, T Baumeister…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 20 p. 5488 - 5497

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被引用次数: 18

摘要

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... 3). In this Letter, we describe the successful identification of indazole-derived NAMPT inhibitors along with their detailed biological and structural characterization. ...