Reaction of 2??dimethylaminomethylene??1, 3??diones with dinucleophiles. V. Synthesis of 5??acyl??1, 2??dihydro??2??oxo??3??pyridinecarbonitriles and 1, 2, 5, 6, 7, 8?? …

L Mosti, P Schenone, C Menozzi

文献索引：Mosti, Luisa; Schenone, Pietro; Menozzi, Giulia Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1503 - 1509

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被引用次数: 30

摘要

Abstract The reaction of open-chain sym-2-dimethylaminomethylene-1, 3-diones Ia-d with sodium cyanoacetamide gave, generally in good yields, 6-substituted 5-acyl-1, 2-dihydro-2- oxo-3-pyridinecarbonitriles IIa-d, whereas cyclohexane sym-2-dimethylaminomethylene-1, 3- diones Ie-h afforded in general a mixture of 1, 2, 5, 6, 7, 8-hexahydro-2, 5-dioxo-3- quinolinecarbonitriles and 5, 6, 7, 8-tetrahydro-2, 5-dioxo-2H-1-benzopyran-3- ...