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Copper??Catalyzed Intramolecular Dehydrogenative Aminooxygenation: Direct Access to Formyl??Substituted Aromatic N??Heterocycles

H Wang, Y Wang, D Liang, L Liu…

文献索引:Wang, Honggen; Wang, Yong; Liang, Dongdong; Liu, Lanying; Zhang, Jiancun; Zhu, Qiang Angewandte Chemie - International Edition, 2011 , vol. 50, # 25 p. 5678 - 5681

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被引用次数: 199

摘要

Aminooxygenation of alkenes,[1–3] a process in which nitrogen and oxygen atoms are added simultaneously across a carbon–carbon double bond, represents one of the most straightforward approaches to prepare vicinal amino alcohol derivatives, which are an important functional motif in many biologically active compounds.[4] The regioselective intramolecular version of this process leads to a variety of nitrogen-containing ...