Tetrahedron: Asymmetry

Candida antarctica lipase A—a powerful catalyst for the resolution of heteroaromatic β-amino esters

M Solymár, F Fülöp, LT Kanerva

文献索引：Solymar, Magdolna; Fueloep, Ferenc; Kanerva, Liisa T. Tetrahedron Asymmetry, 2002 , vol. 13, # 21 p. 2383 - 2388

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被引用次数: 37

摘要

Enantioselective acylations of 3-amino-3-heteroarylpropanoates (ArCH (NH2) CH2CO2Et; Ar= 2-or 3-thienyl or-furyl) were performed in the presence of Candida antarctica lipase A. As a result of the excellent chemo-and enantioselectivities (E> 100), gram-scale ...