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Study of regioselectivity of reactions between 3 (5)-aminopyrazoles and 2-acetylcycloalkanones

AA Petrov, AN Kasatochkin, EE Emelina

文献索引:Petrov; Kasatochkin; Emelina Russian Journal of Organic Chemistry, 2012 , vol. 48, # 8 p. 1111 - 1120 Zh. Org. Khim., 2012 , vol. 48, # 8 p. 1113 - 1121,9

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被引用次数: 5

摘要

Abstract Regioselectivity was examined of reactions between nine 3 (5)-aminopyrazoles and 2-acetylcyclopentanone and 2-acetylcyclohexanone under various conditions. A series of cyclopenta [e] pyrazolo-[1, 5-a] pyrimidines was obtained. The highest regioselectivity of the reaction was observed in alcohol at 20° C in the presence of a catalytic quantity of trifl uoroacetic acid. The regiostructure of compounds was established by 1 H and 13 C NMR ...