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Synthesis and Antimicrobial Activity of Novel Heterocyclic Sulfamoyl??phenyl??carboximidamides Derived from Clinically Applied Sulfonamides

…, E Augustynowicz??Kopeć, A Napiórkowska

文献索引:Gobis, Katarzyna; Foks, Henryk; Wisniewska, Katarzyna; Dabrowska-Szponar, Maria; Augustynowicz-Kopec, Ewa; Napiorkowska, Agnieszka Archiv der Pharmazie, 2012 , vol. 345, # 11 p. 911 - 917

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被引用次数: 3

摘要

Abstract A series of novel heterocyclic sulfamoyl-phenyl-carboximidamides were synthesized in satisfactory yields via condensation of clinically applied sulfonamides with heterocyclic methyl carbimidates. New structures were confirmed by IR and NMR spectra as well as elemental analyses. All the compounds were screened for their antibacterial, antifungal, and tuberculostatic activities. Preliminary results indicated that some target ...