Design and synthesis of cinanserin analogs as severe acute respiratory syndrome coronavirus 3CL protease inhibitors

Q Yang, L Chen, X He, Z Gao, X Shen…

文献索引：Yang, Qingang; Chen, Lili; He, Xuchang; Gao, Zhenting; Shen, Xu; Bai, Donglu Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 10 p. 1400 - 1405

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被引用次数: 13

摘要

The severe acute respiratory syndrome (SARS) coronavirus 3CL protease is an attractive target for the development of anti-SARS drugs. In this paper, cinanserin (1) analogs were synthesized and tested for the inhibitory activities against SARS-coronavirus (CoV) 3CL ...