Synthesis of pyrano-and furanopyrimidines from 3-halopropyl and 2-halopropylbarbituric acids

EE Smissman, RA Robinson…

文献索引：Smissman,E.E. et al. Journal of Organic Chemistry, 1970 , vol. 35, # 11 p. 3823 - 3824

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被引用次数: 11

摘要

In attempts to obtain intramolecular N-alkylated bioyclo compounds from 5- haloalkylbarbituric acids, only 0-alkylated compounds could be obtained. The resulting pyranopyrimidine, 7, and furanopyrimidine, 9, could be opened with alcohols to give the corresponding ether in the side chain of the barbituric acid. With water the side chain alcohol wm obtained.