Biomimetic syntheses of the polyketide fungal metabolites alternariol and rubrofusarin: models for cyclisation reactions catalysed by polyketide synthase enzymes
C Abell, BD Bush, J Staunton
文献索引：Abell, Chris; Bush, Brian D.; Staunton, James Journal of the Chemical Society, Chemical Communications, 1986 , # 1 p. 15 - 17
Various phenolic polyketone derivatives containing thioester groups, closely analogous in structure to proposed thioester intermediates bound to polyketide synthase enzymes, undergo highly regioselective biomimetic cyclisations to form one or the other of the heptaketide metabolites, rubrofusarin and alternariol methyl ether.
