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Copper-catalyzed arylation of phenylurea using KF/Al 2 O 3

…, Y Sarrafi, M Mohadjerani, F Mohammadpourmir

文献索引:Hosseinzadeh, Rahman; Sarrafi, Yaghoub; Mohadjerani, Maryam; Mohammadpourmir, Fatemeh Tetrahedron Letters, 2008 , vol. 49, # 5 p. 840 - 843

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被引用次数: 39

摘要

A mild and efficient method for the copper-catalyzed arylation of phenylurea is described. The coupling reaction of phenylurea with different functionalized aryl iodides in the presence of air stable CuI, N, N′-dibenzylethylenediamine as a ligand, and KF/Al2O3 as a base gives symmetrical and unsymmetrical diarylureas in relatively high yields.