Decomposition of Sodium Trichloroacetate in the Presence of Quaternary Ammonium under Microwave Irradiation: A Convenient One??Pot Synthesis of α??Hydroxy …
Abstract A good yielding phase??transfer??catalyzed procedure for one??pot preparation of α?? hydroxy acids from carbonyl compounds and sodium trichloroacetate by in situ addition and hydrolysis under microwave irradiation is described. Decomposition of sodium trichloroacetate is strongly accelerated by the presence of quaternary ammonium. The reaction can be conducted in water.
