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A New Synthesis of Flavone Involving Cyclization via Displacement of Aromatic Chlorine

PL Southwick, JR Kirchner

文献索引:Southwick; Kirchner Journal of the American Chemical Society, 1957 , vol. 79, p. 689

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被引用次数: 0

摘要

We wish to describe the results of the initial investigation of a new cyclization reaction which can be used for the preparation of flavone (VI) and probably will prove applicable to the synthesis of some types of substituted flavones. The cyclization in question occurs when P- morpholino-2-chlorochalcone (11) is heated to the proper ternperature in a solvent. The initial reaction product is not flavone itself but a related salt, 4-morpholinoflavyliurn ...