Chemistry letters

N-alkylation of phthalimide, carboxamide, and sulfonamides by oxdation-reduction condensation using Di-tert-butyl-1, 4-benzoquinone and alkyl diphenylphosphinite

T Mukaiyama, H Aoki

文献索引：Mukaiyama, Teruaki; Aoki, Hidenori Chemistry Letters, 2005 , vol. 34, # 2 p. 142 - 143

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被引用次数: 17

摘要

It was recently reported from our laboratory that a new type of oxidation–reduction condensation using alkyl diphenyl- phosphinite (Ph2POR) formed from n-BuLi-treated alcohols and chlorodiphenylphosphine, 2,6-dimethyl-1,4-benzoquinone (DMBQ) and carboxylic acids afforded alkyl carboxylates from alcohols including chiral tertiary ones in good to high yields with inversion of configurations in high levels (up to >99:9% inver- sion).1 This method was further ...