Synlett

Efficient Synthesis of Phenanthridines Using Hendrickson Reagent Initiated Cascade Reaction under Mild Conditions

J Xi, QL Dong, GS Liu, S Wang, L Chen, ZJ Yao

文献索引：Xi, Jie; Dong, Qing-Li; Liu, Guan-Sai; Wang, Shaozhong; Chen, Lin; Yao, Zhu-Jun Synlett, 2010 , # 11 p. 1674 - 1678

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被引用次数: 11

摘要

Abstract A number of variously substituted phenanthridines have been synthesized using the newly developed methodology under mild conditions. The Hendrickson reagent initiated cascade annulation, which is composed of a mild conversion of stable amide precursor to highly reactive imido-carbonium intermediate and a subsequent intramolecular Friedel- Crafts reaction, successfully served as the key method.