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Antiviral, metabolic, and pharmacokinetic properties of the isomeric dideoxynucleoside 4 (S)-(6-amino-9H-purin-9-yl) tetrahydro-2 (S)-furanmethanol.

V Nair, MH St Clair, JE Reardon…

文献索引:Antimicrobial Agents and Chemotherapy, , vol. 39, # 9 p. 1993 - 1999

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被引用次数: 61

摘要

Page 1. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Sept. ... Thus, IsoddA was a minimally selective anti-HBV agent in this in vivo chemotherapy model. In vitro cytotoxicity. ... Novel isomeric dideoxynucleosides as potential antiviral agents. Tetrahedron 50: 7747–7764. ...