Rational design of fluorescein-based fluorescence probes. Mechanism-based design of a maximum fluorescence probe for singlet oxygen

K Tanaka, T Miura, N Umezawa, Y Urano…

文献索引：Tanaka; Miura; Umezawa; Urano; Kikuchi; Higuchi; Nagano Journal of the American Chemical Society, 2001 , vol. 123, # 11 p. 2530 - 2536

全文：HTML全文

被引用次数: 299

摘要

Fluorescein is one of the best available fluorophores for biological applications, but the factors that control its fluorescence properties are not fully established. Thus, we initiated a study aimed at providing a strategy for rational design of functional fluorescence probes bearing fluorescein structure. We have synthesized various kinds of fluorescein derivatives and examined the relationship between their fluorescence properties and the highest ...