Tetrahedron letters

Ionic liquid enabled sulfamoylation of arenes: an ambient, expeditious and regioselective protocol for aryl sulfonamides

PU Naik, JR Harjani, SJ Nara, MM Salunkhe

文献索引：Naik, Prashant U.; Harjani, Jitendra R.; Nara, Susheel J.; Salunkhe, Manikrao M. Tetrahedron Letters, 2004 , vol. 45, # 9 p. 1933 - 1936

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被引用次数: 15

摘要

The ionic liquid, 1-butyl-3-methylimidazolium chloroaluminate,[bmim] Cl· AlCl3, N= 0.67 mediated syntheses of aromatic sulfonamides via electrophilic substitution of arenes is reported. The protocol serves as a distinctly expeditious and ambient route towards the syntheses of these pharmaceutically useful compounds, yielding quantitative conversions at room temperature within 5–30min in most of the cases. The Lewis acidity and molar ...