Synthesis of novel thiazolo [5, 4-d] pyrimidines

G Chattopadhyay, D Saha, P Sinha Ray…

文献索引：Chattopadhyay, Gautam; Saha, Debnath; Ray, Partha Sinha; Naskar, Subhendu; Sarkar, Swarbhanu Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010 , vol. 49, # 9 p. 1229 - 1234

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被引用次数: 5

摘要

Abstract: 2-Methylsulphanyl-5-aminothiazole-4-carboxamide 1 has been used as a convenient precursor for the synthesis of new thiazolo [4, 5-e][1, 2, 4-triazolo][4, 3-c] pyrimidines 5 and the corresponding tetrazolo analogue 7. A mesoionic isomer 8 seems to exist along with 7. Interesting heteroarylthiazolo pyrimidine motifs have also been prepared via suitably substituted thiazolo [5, 4-d] pyrimidines.