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The Journal of Organic Chemistry

Novel approach to lactams via (triisopropylsilyl) azidohydrin formation and photoinduced Schmidt rearrangement

PA Evans, DP Modi

文献索引:Evans, P. Andrew; Modi, Dilip P. Journal of Organic Chemistry, 1995 , vol. 60, # 21 p. 6662 - 6663

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被引用次数: 21

摘要

Lactams are particularly important molecules owing to their versatility as synthetic intermediates and widespread occurrence in biologically important compounds. lv2 They have also proven extremely informative as transition state models in amide reactivity~ tudies.~ Despite the development of a variety of new methods, 4s5 the Schmidt6 and Beckmann7 reactions remain the most convenient and general protocols for their ...