Preparation of functionalized arylmagnesium reagents bearing an o-chloromethyl group

…, L Bérillon, G Cahiez, P Knochel

文献索引：Delacroix; Berillon; Cahiez; Knochel Journal of Organic Chemistry, 2000 , vol. 65, # 23 p. 8108 - 8110

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被引用次数: 49

摘要

The iodine-magnesium exchange is a unique method for the preparation of polyfunctional organomagnesium reagents. 1, 2 The efficient reaction of i-PrMgX with a wide range of functionalized aryl iodides proceeds under mild conditions so that various sensitive functional groups such as an ester, a nitrile, or an amide function are tolerated during the organomagnesium reagent formation. This method complements nicely the classical ...