The Journal of Organic Chemistry

The Condensation of Phosphonic Dichlorides with o-Diamines

RL DANNLEY, PL WAGNER

文献索引：Dannley,R.L.; Wagner,P.L. Journal of Organic Chemistry, 1961 , vol. 26, p. 3995 - 3997

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被引用次数: 9

摘要

Current interest has been developed in analogs of naturally occurring purines because of their potential use as antimetabolites, particularly in cancer chemotherapy. The present work is concerned with the synthesis of dihydro-1, 3, 2-diazaphospholes by the reactions of phosphonic dichlorides with o-diamines. The dihydrodiazaphosphole ring may be considered an imidazoline system, spatially similar to the imidazoles, in which ...