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Tetrahedron Letters

Intramolecular glycosylation as a regio-and stereocontrolled approach for the synthesis of 8-oxo-purine nucleosides

H Sugimura, D Nitta

文献索引:Sugimura, Hideyuki; Nitta, Daisuke Tetrahedron Letters, 2012 , vol. 53, # 33 p. 4460 - 4463

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被引用次数: 3

摘要

On the other hand, we previously reported the development of a convenient method for the stereocontrolled synthesis of pyrimidine nucleosides that utilizes an intramolecular aglycon delivery system. 5 An important feature of this method is that it uses 1-thioglycosides as glycosyl donors, which can be considered stable glycosides during the step involving modification of the carbohydrate moieties as well as during the introduction of the pyrimidine base, whereas the 1- ...