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Tetrahedron Letters

Highly efficient synthesis of polysubstituted fluorene via iron-catalyzed intramolecular Friedel–Crafts alkylation of biaryl alcohols

S Sarkar, S Maiti, K Bera, S Jalal, U Jana

文献索引:Sarkar, Soumen; Maiti, Sukhendu; Bera, Krishnendu; Jalal, Swapnadeep; Jana, Umasish Tetrahedron Letters, 2012 , vol. 53, # 41 p. 5544 - 5547

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被引用次数: 21

摘要

An efficient and mild Fe (III)-catalyzed intramolecular Friedel–Crafts alkylation of biaryl methanol derivatives has been developed to achieve the substituted fluorene derivatives. The present reaction provides an excellent alternative to published methods because of its high yields, operational simplicity, mild conditions, and use of inexpensive and sustainable catalyst.