Tetrahedron Letters

Mixing with microwaves: solvent-free and catalyst-free synthesis of pyrazoles and diazepines

BR Vaddula, RS Varma, J Leazer

文献索引：Vaddula, Buchi Reddy; Varma, Rajender S.; Leazer, John Tetrahedron Letters, 2013 , vol. 54, # 12 p. 1538 - 1541

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被引用次数: 24

摘要

A simple and facile condensation of hydrazines/hydrazides and diamines with 1, 3- diketones/β-ketoester leads to the preparation of pyrazoles and diazepines in high yields. This eco-friendly protocol is accelerated by microwave heating and efficiently carried out without any reaction solvent or catalyst in as little as 5min.