Chemistry Letters

Unexpected Extension of Usage of PPh 3/CBr 4, a Versatile Reagent: Isomerization of Aromatic Allylic Alcohols

W Gong, Y Liu, J Xue, Z Xie, Y Li

文献索引：Gong, Wanchun; Liu, Yun; Xue, Jijun; Xie, Zhixiang; Li, Ying Chemistry Letters, 2012 , vol. 41, # 12 p. 1597 - 1599

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被引用次数: 4

摘要

The PPh 3/CBr 4-catalyzed isomerization of 2-aromatic allylic alcohols into the corresponding saturated aldehydes or ketones has been achieved at room temperature in good to excellent yields under mild and metal-free conditions. This new methodology has been applied successfully to the synthesis of ibuprofen in four steps.