Site??specific labelling of caged atp with deuterium or 18oxygen

JET Corrie, GP Reid

文献索引：Corrie; Reid Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 3 p. 289 - 300

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被引用次数: 5

摘要

Abstract [3-D] 2-Nitroacetophenone and [alcohol-18 O]-1-(2-nitrophenyl) ethyl alcohol were prepared and used to synthesise labelled P 3-l-(2-nitrophenyl) ethyl esters of ATP (“caged ATP”) with isotope present either as deuterium on the 3-position of the nitrosubstituted ring or as 18 oxygen in the bridging position between the terminal phosphate and the nitrophenylethyl group. The availability of the deuterated compounds enabled complete ...