Tetrahedron

Synthesis of 3, 5-bis (phosphonomethyl) benzoic acid and its application as a metal oxide surface bivalent anchor

…, SA Trammell, KM Sigel, TJ Meyer, BW Erickson

文献索引：Nakhle, Bassam M.; Trammell, Scott A.; Sigel, Keith M.; Meyer, Thomas J.; Erickson, Bruce W. Tetrahedron, 1999 , vol. 55, # 10 p. 2835 - 2846

全文：HTML全文

被引用次数: 17

摘要

A protected form of 3, 5-bis (phosphonomethyl) benzoic acid (Bpb-OH), a metal oxide surface bivalent anchor, has been synthesized, coupled to an amine functionality, deprotected, and shown to bind to metal oxide surfaces. The protected anchor, 3, 5-bis ( dimethoxyphosphinylmethyl) benzoic acid (Me4Bpb-OH) was synthesized in 23% yield over four steps, coupled to a proline-chromophore, deprotected with a solution of ...