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Pyrazolopyrimidine nucleosides. V. Methylation of the C-nucleoside antibiotic formycin and structural elucidation of products by magnetic circular dichroism …

LB Townsend, RA Long, JP McGraw…

文献索引:Townsend,L.B. et al. Journal of Organic Chemistry, 1974 , vol. 39, p. 2023 - 2027

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被引用次数: 27

摘要

The antibiotics formycin and formycin B were isolated3 from Norcardia interforma and f~ und~-~ to be C-nucleosides which were isomeric with the naturally occurring nucleosides adenosine and inosine, respectively. These antibiotics are of considerable interest since they are C-nucleosides and belong to the same class of compounds as~ howdomycin,~ pseudouridine, 8 and pyra~ omycin.~ Formycin has demonstrated inhibition of Ehrlich ...