Bioorganic & medicinal chemistry

Design, development and synthesis of mixed bioconjugates of piperic acid–glycine, curcumin–glycine/alanine and curcumin–glycine–piperic acid and their …

S Mishra, U Narain, R Mishra, K Misra

文献索引：Mishra, Satyendra; Narain, Upma; Mishra, Roli; Misra, Krishna Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1477 - 1486

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被引用次数: 134

摘要

In the present communication different curcumin bioconjugates viz. 4, 4′-di-O-glycinoyl- curcumin, 4, 4′-di-Od-alaninoyl-curcumin, 4, 4′-di-O-(glycinoyl-di-N-piperoyl)-curcumin, 4, 4′-di-O-piperoyl curcumin, curcumin-4, 4′-di-O-β-d-glucopyranoside, 4, 4′-di-O-acetyl- curcumin along with piperoyl glycine, have been synthesised and characterised by spectra UV, 1H NMR and elemental analysis. All the covalent bonds used are biodegradable. This ...