Steroids

Phosphonic acids—X steroidal phosphonic esters

RG Harvey, ER DeSombre, EV Jensen

文献索引：Harvey,R.G. et al. Steroids, 1967 , vol. 9, p. 101 - 111

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被引用次数: 1

摘要

Abstract Steroidal phosphonate esters having the dialkoxyphosphinyl group,(RO) 2 P (O)-, as a ring substituent have been synthesized via reaction of the appropriate α, β-unsaturated ketosteroid with trialkyl phosphite in alcohol. By this means a phosphorus substituent has been introduced into the 1-positions of testosterone, hydrocortisone, and cortisone, into the 7-position of testosterone and into the 16-positions of pregnenolone and progesterone. ...