[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate

Modify Date: 2024-04-05 14:19:57

[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate structure	Common Name	[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate
	CAS Number	981-01-1	Molecular Weight	369.41100
	Density	1.35g/cm3	Boiling Point	514.5ºC at 760 mmHg
	Molecular Formula	C₂₁H₂₃NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	265ºC

Name	[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate
Synonym	More Synonyms

Density	1.35g/cm3
Boiling Point	514.5ºC at 760 mmHg
Molecular Formula	C₂₁H₂₃NO₅
Molecular Weight	369.41100
Flash Point	265ºC
Exact Mass	369.15800
PSA	65.07000
LogP	1.72300
Index of Refraction	1.631

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD2167000

CHEMICAL NAME :: Morphinan-6-one, 7,8-didehydro-4,5-alpha-epoxy-14-hydroxy-3-methoxy-17 -methyl-, propionate (ester)

CAS REGISTRY NUMBER :: 981-01-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C21-H23-N-O5

MOLECULAR WEIGHT :: 369.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 110 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964

(4R,4aS,7S,7aR,...

CAS#:4829-46-3

[(4R,4aS,7aR,12...

CAS#:981-01-1

Literature: Currie,A.C. et al. Journal of the Chemical Society, 1960 , p. 773 - 781

14-hydroxycodei...

CAS#:103458-67-9

[(4R,4aS,7aR,12...

CAS#:981-01-1

Literature: Currie,A.C. et al. Journal of the Chemical Society, 1960 , p. 773 - 781

6α-acetoxy-4,5α...

CAS#:100740-63-4

[(4R,4aS,7aR,12...

CAS#:981-01-1

Literature: Currie,A.C. et al. Journal of the Chemical Society, 1960 , p. 773 - 781

14-Hydroxy Codeinone

CAS#:508-54-3

Propionic anhydride

CAS#:123-62-6

[(4R,4aS,7aR,12...

CAS#:981-01-1

Literature: Currie,A.C. et al. Journal of the Chemical Society, 1960 , p. 773 - 781

Precursor 5
CAS#:4829-46-3 (4R,4aS,7S,7aR,... CAS#:103458-67-9 14-hydroxycodei... CAS#:100740-63-4 6α-acetoxy-4,5α... CAS#:508-54-3 14-Hydroxy Codeinone
CAS#:123-62-6 Propionic anhydride
DownStream 0

14-Propionyloxy-kodeinon

14-Propionyloxycodeinon

Codeinone,14-hydroxy-,propionate

Morphinan-6-one,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-14-(1-oxopropoxy)-,(5alpha)

Morphinan-6-one,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-14-(1-oxopropoxy)-,(5)

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3

[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms