14-Hydroxy Codeinone

Modify Date: 2024-01-04 08:32:15

14-Hydroxy Codeinone Structure
14-Hydroxy Codeinone structure
Common Name 14-Hydroxy Codeinone
CAS Number 508-54-3 Molecular Weight 313.34800
Density 1.433g/cm3 Boiling Point 512.176ºC at 760 mmHg
Molecular Formula C18H19NO4 Melting Point 275°C (rough estimate)
MSDS N/A Flash Point 263.555ºC
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name 14-Hydroxy Codeinone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.433g/cm3
Boiling Point 512.176ºC at 760 mmHg
Melting Point 275°C (rough estimate)
Molecular Formula C18H19NO4
Molecular Weight 313.34800
Flash Point 263.555ºC
Exact Mass 313.13100
PSA 59.00000
LogP 1.35280
Index of Refraction 1.684

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GG8225000
CHEMICAL NAME :
Codeinone, 14-hydroxy-
CAS REGISTRY NUMBER :
508-54-3
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H19-N-O4
MOLECULAR WEIGHT :
313.38
WISWESSER LINE NOTATION :
T B6566 B6/CO 4ABBC R BX FV HO PN DU GHT&&TTJ CQ JO1 P1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
23 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,27,1938
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
11800 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300 + H310 + H330
Precautionary Statements Missing Phrase - N15.00950417-P260-P262-P280-P302 + P352 + P310-P304 + P340 + P310
RIDADR NONH for all modes of transport

 Synthetic Route

 Synonyms

4-(9b-ethyl-5-methoxy-1,2,3,3a,8,9,9a,9b-octahydro-phenanthro[4,5-bcd]furan-3-yl)-morpholine
Morpholine,4-(9bb-ethyl-1,2,3,3ab,8,9,9ab,9b-octahydro-5-methoxyphenanthro[4,5-bcd]furan-3-yl)-(8CI)
Oxycodone impurity D
Morpholine,4-(9b-ethyl-1,2,3,3a,8,9,9a,9b-octahydro-5-methoxyphenanthro[4,5-bcd]furan-3-yl)-,[3S-(3a,3ab,9ab,9bb)]-(9CI)
14-hydroxy-codeinone
Morpholine,4-(9bb-ethyl-1,2,3,3a,8,9,9ab,9b-octahydro-5-methoxyphenanthro[4,5-bcd]furan-3a-yl)-(7CI)