STAT3 inhibitor C188
Modify Date: 2024-04-08 12:06:09
STAT3 inhibitor C188 structure
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Common Name | STAT3 inhibitor C188 | ||
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| CAS Number | 823828-18-8 | Molecular Weight | 433.449 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H15NO7S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of STAT3 inhibitor C188A potent, selective STAT3 inhibitor that blocks STAT3 binding to its phosphopeptide ligand (IC50=20 uM) and inhibits IL-6-mediated phosphorylation of STAT3; inhibits nuclear translocation of phosphorylated Stat3 with IC50 of 39 uM, induces apoptosis preferentially of breast cancer cell lines with constitutive Stat3 activation. |
| Name | STAT3 inhibitor C188 |
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| Description | A potent, selective STAT3 inhibitor that blocks STAT3 binding to its phosphopeptide ligand (IC50=20 uM) and inhibits IL-6-mediated phosphorylation of STAT3; inhibits nuclear translocation of phosphorylated Stat3 with IC50 of 39 uM, induces apoptosis preferentially of breast cancer cell lines with constitutive Stat3 activation. |
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| References | References 1. Xu X, et al. PLoS One. 2009;4(3):e4783. View Related Products by Target STAT |
| Molecular Formula | C19H15NO7S2 |
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| Molecular Weight | 433.449 |