Andrographoside

Modify Date: 2024-01-11 12:54:34

Andrographoside Structure
Andrographoside structure
Common Name Andrographoside
CAS Number 82209-76-5 Molecular Weight 512.590
Density 1.4±0.1 g/cm3 Boiling Point 747.2±60.0 °C at 760 mmHg
Molecular Formula C26H40O10 Melting Point N/A
MSDS USA Flash Point 247.2±26.4 °C

 Use of Andrographoside


Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP)[1].

 Names

Name Andrographoside
Synonym More Synonyms

 Andrographoside Biological Activity

Description Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP)[1].
Related Catalog
References

[1]. Kapil A, et al. Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata. Biochem Pharmacol. 1993 Jul 6;46(1):182-5.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 747.2±60.0 °C at 760 mmHg
Molecular Formula C26H40O10
Molecular Weight 512.590
Flash Point 247.2±26.4 °C
Exact Mass 512.262146
PSA 166.14000
LogP -0.41
Vapour Pressure 0.0±5.6 mmHg at 25°C
Index of Refraction 1.602
Storage condition ?20°C

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synonyms

[(1R,2R,4aS,5R,8aS)-2-Hydroxy-5-{(2E)-2-[(4S)-4-hydroxy-2-oxodihydro-3(2H)-furanylidene]ethyl}-1,4a-dimethyl-6-methylenedecahydro-1-naphthalenyl]methyl β-D-glucopyranoside
2(3H)-Furanone, 3-[2-[(1R,4aS,5R,6R,8aS)-5-[(β-D-glucopyranosyloxy)methyl]decahydro-6-hydroxy-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, (3E,4S)-
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