DTSSP Crosslinker

Modify Date: 2024-01-11 16:38:49

DTSSP Crosslinker Structure
DTSSP Crosslinker structure
Common Name DTSSP Crosslinker
CAS Number 81069-02-5 Molecular Weight 564.54200
Density 1.94 Boiling Point N/A
Molecular Formula C14H16N2O14S4 Melting Point N/A
MSDS USA Flash Point N/A

 Use of DTSSP Crosslinker


DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 3,3'-Dithiobis(sulfosuccinimidylpropionate)
Synonym More Synonyms

 DTSSP Crosslinker Biological Activity

Description DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Density 1.94
Molecular Formula C14H16N2O14S4
Molecular Weight 564.54200
Exact Mass 563.94800
PSA 303.46000
LogP 0.13240
Index of Refraction 1.693

 Safety Information

Hazard Codes Xi
Safety Phrases 26-36

 Synonyms

N,N'-dioctyl-3,3'-disulfanediyl-bis-propionamide
N,N'-Bis-n-octyl-3,3'-dithiopropionamide
3,3'-disulfanediylbis(N-octylpropanamide)
3,3-dithiobis(sulfosuccinimidyl propionate)
N,N'-di-n-octyl-3,3'-dithiodipropionamide
N,N'-Di-n-octyl-3,3'-dithiodipropionamid
Propanamide,3,3'-dithiobis[N-octyl
(SCH2CH2CONHC8H17)2
3,3'-dithiobis(N-octylpropionamide)
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