NSC45586 free base

Modify Date: 2024-01-13 12:54:08

NSC45586 free base Structure
NSC45586 free base structure
Common Name NSC45586 free base
CAS Number 739301-85-0 Molecular Weight 390.403
Density N/A Boiling Point N/A
Molecular Formula C20H18N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NSC45586 free base


NSC45586 free base (NCS 45586, NCI45586) is a potent, specific PHLPP2 inhibitor with IC50 of 4 uM, targets the PHLPP2 PP2C domain, suppresses MYC and triggers cell death.

 Names

Name NSC45586 free base

 NSC45586 free base Biological Activity

Description NSC45586 free base (NCS 45586, NCI45586) is a potent, specific PHLPP2 inhibitor with IC50 of 4 uM, targets the PHLPP2 PP2C domain, suppresses MYC and triggers cell death.
References 1. Nowak DG, et al. J Cell Biol. 2019 May 15. pii: jcb.201902048. doi: 10.1083/jcb.201902048.

 Chemical & Physical Properties

Molecular Formula C20H18N6O3
Molecular Weight 390.403