NSC45586 free base

Names

[ Name ]:
NSC45586 free base

Biological Activity

[Description]:

NSC45586 free base (NCS 45586, NCI45586) is a potent, specific PHLPP2 inhibitor with IC50 of 4 uM, targets the PHLPP2 PP2C domain, suppresses MYC and triggers cell death.

[References]

1. Nowak DG, et al. J Cell Biol. 2019 May 15. pii: jcb.201902048. doi: 10.1083/jcb.201902048.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₈N₆O₃

[ Molecular Weight ]:
390.403

Related Compounds

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