2-Hydroxyoctanoic acid

Modify Date: 2024-01-02 18:20:58

2-Hydroxyoctanoic acid Structure
2-Hydroxyoctanoic acid structure
Common Name 2-Hydroxyoctanoic acid
CAS Number 617-73-2 Molecular Weight 160.21
Density 1.0±0.1 g/cm3 Boiling Point 289.0±13.0 °C at 760 mmHg
Molecular Formula C8H16O3 Melting Point 66-68 °C
MSDS Chinese USA Flash Point 142.8±16.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2-Hydroxyoctanoic acid


2-Hydroxyoctanoic acid is a medium chain acyl-CoA synthetase inhibitor with a Ki of 500 μM[1].

 Names

Name 2-hydroxyoctanoic acid
Synonym More Synonyms

 2-Hydroxyoctanoic acid Biological Activity

Description 2-Hydroxyoctanoic acid is a medium chain acyl-CoA synthetase inhibitor with a Ki of 500 μM[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. F Kasuya, et al. Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids. Biochem Pharmacol. 1996 Nov 22;52(10):1643-6.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 289.0±13.0 °C at 760 mmHg
Melting Point 66-68 °C
Molecular Formula C8H16O3
Molecular Weight 160.21
Flash Point 142.8±16.3 °C
Exact Mass 160.109940
PSA 57.53000
LogP 1.96
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.463
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918199090

 Synthetic Route

 Customs

HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles4

More Articles
Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids.

Biochem. Pharmacol. 52 , 1643-1646, (1996)

Molecular characteristics of carboxylic acids were investigated for the ability to inhibit a purified medium chain acyl-CoA synthetase, using hexanoic acid as a substrate. Salicylic acid, 4-methylsali...

Determination of the enantiomers of alpha-hydroxy- and alpha-amino acids in capillary electrophoresis with contactless conductivity detection.

Electrophoresis 31 , 2044-2048, (2010)

The enantiomers of the anions of five alpha-hydroxy acids, namely lactic acid, alpha-hydroxybutyric acid, 2-hydroxycaproic acid, 2-hydroxyoctanoic acid and 2-hydroxydecanoic acid, as well as the two a...

3-Hydroxydicarboxylic aciduria due to long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency associated with sudden neonatal death: protective effect of medium-chain triglyceride treatment.

Eur. J. Pediatr. 150(3) , 190-5, (1991)

Two siblings were found to be affected by long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency, one of which died suddenly and unexpectedly on the 3rd day of life suffering from extreme hypoketotic h...

 Synonyms

a-Hydroxyoctanoic acid
Hexadecanoic acid,2-hydroxy
EINECS 210-524-3
2-hydroxy-n-octanoic acid
dl-A-hydroxypalmitic acid
2-hydroxypalmitic acid
hydroxyhexadecanoic acid
hydroxycaprylic Acid
α-Hydroxyoctanoic acid
DL-2-Hydroxycaprylic acid
DL-2-Hydroxyoctanoic acid
hydrogen carbonate (bicarbonate)
a-Hydroxycaprylic acid
D,L-2-hydroxyhexadecanoic acid
Octanoic acid, 2-hydroxy-
UNII:0R6X0G0S8A
monohydroxymonocarboxylic acid
HYDROXYPALMITIC ACID,2
2-HYDROXY C16:0 ACID
MFCD00014410
Hydroxypalmiticacid
2-Hydroxyoctanoic Acid
2-Hydroxycaprylic acid
Hydroxyoctanoic acid
(+/-)-2-HYDROXYHEXADECANOIC ACID