VU0152099
Modify Date: 2024-04-05 09:52:49
VU0152099 structure
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Common Name | VU0152099 | ||
|---|---|---|---|---|
| CAS Number | 612514-42-8 | Molecular Weight | 355.411 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 622.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C18H17N3O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 330.5±31.5 °C | |
Use of VU0152099VU0152099 is a potent, selective, CNS-penetrant positive allosteric modulator of M4 mAChR with EC50 of 403 nM; shows no agonist activity but potentiates responses of M(4) to acetylcholine, and is devoid of activity at other mAChR subtypes or at a panel of other GPCRs; reverses amphetamine-induced hyperlocomotion in rats. |
| Name | VU0152099 |
|---|---|
| Synonym | More Synonyms |
| Description | VU0152099 is a potent, selective, CNS-penetrant positive allosteric modulator of M4 mAChR with EC50 of 403 nM; shows no agonist activity but potentiates responses of M(4) to acetylcholine, and is devoid of activity at other mAChR subtypes or at a panel of other GPCRs; reverses amphetamine-induced hyperlocomotion in rats. |
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| References | References 1. Brady AE, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):941-53. View Related Products by Target mAChR |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 622.9±55.0 °C at 760 mmHg |
| Molecular Formula | C18H17N3O3S |
| Molecular Weight | 355.411 |
| Flash Point | 330.5±31.5 °C |
| Exact Mass | 355.099060 |
| LogP | 4.32 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.708 |
| 3-Amino-N-(1,3-benzodioxol-5-ylmethyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide |
| Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-(1,3-benzodioxol-5-ylmethyl)-4,6-dimethyl- |
| VU0152099 |