1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE

Modify Date: 2024-01-09 08:03:27

1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE Structure
1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE structure
Common Name 1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE
CAS Number 60569-19-9 Molecular Weight 367.48
Density 1.08 g/cm3 Boiling Point 468.8ºC at 760 mmHg
Molecular Formula C23H29NO3 Melting Point N/A
MSDS N/A Flash Point 134.6ºC

 Use of 1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE


Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2].

 Names

Name (1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate
Synonym More Synonyms

  Biological Activity

Description Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2].
Related Catalog
References

[1]. McKeage K. Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms. Clin Drug Investig. 2013 Jan;33(1):71-91.

[2]. Madersbacher H, Mürtz G. Efficacy, tolerability and safety profile of propiverine in the treatment of the overactive bladder (non-neurogenic and neurogenic). World J Urol. 2001 Nov;19(5):324-35.

 Chemical & Physical Properties

Density 1.08 g/cm3
Boiling Point 468.8ºC at 760 mmHg
Molecular Formula C23H29NO3
Molecular Weight 367.48
Flash Point 134.6ºC
Exact Mass 367.21500
PSA 38.77000
LogP 3.93210
Index of Refraction 1.57

 Safety Information

HS Code 2933399090

 Synthetic Route

~%

1-METHYLPIPERIDIN-4-YL 2,2-DIPHENYL-2-PROPOXYACETATE Structure

1-METHYLPIPERID...

CAS#:60569-19-9

Literature: WO2014/39627 A1, ; Page/Page column 126 ;

 Precursor & DownStream

Precursor  1

DownStream  1

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Propiverine
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